Medicines for face pain

Medicines for face pain treatment

Medicines for face pain treatment are generally those that are used to treat fits (convulsions, seizures). These come under the group called anti-convulsants (these numb the brain and prevent response to stimuli). Anti-convulsants are medicines used to control convulsions(or “fits”).

While there are many medicines that could be used, some are similar to the older versions, some are very different; and some medicines are not related at all. Acupressure, acupuncture, Ayurveda and Homeopathy have also been tried.

How do medicines act?

Basically, all act by numbing the brain (Central nervous system ). The intention is to reduce reactivity of the Trigeminal nerve, but no medicine can act on just one nerve. It therefore acts on the entire nervous system, numbing it. This is the primary reason for the major side-effects of medication.

So, for most people, medication is the first line of treatment. Most of them are off-label  for the treatment of facial pain (Trigeminal Neuralgia). Most patients need to adjust the medication with varying combinations and dosages to get the best pain relief effect with minimal side-effects.

The following video describes the typical journey of a patient who has started having facial pain on one side of the face:

Which medicines are commonly used to treat face pain?

Among the medicines that are used for treatment of trigeminal neuralgia and face pain are

Carbamazepine/Oxcarbamazepine/Eslicarbamazepine,

Gabapentin/Pregabalin,

Phenytoin and other anti-convulsants,

Some anti-depressants,

Skeletal muscle relaxants,

Anaesthetics

Toxins.

These medicines have different formulations and trade names.

How are medicines to treat TN pain started?

Initially only one drug is generally started, at a small dose, then the dose is increased as necessary. If the pain continues to increase in intensity and frequency, a second or third drug may be added. Please be sure to talk to your doctor about the effect and side-effects that you experience. Please look out for rashes or itching or some other sign that you maybe allergic to the drug.

Are there any specific drugs for TN pain?

There is a new drug that is being developed specifically for trigeminal neuralgia pain. Research is still on, and it is in the planning stage.

Please be sure to talk to your doctor about the effect and side-effects that you experience.

What are the side-effects of medicines used to treat face pain?

Common side effects of Medicines used for treatment of facial pain:

Memory loss

Reduced co-ordination

Confusion

Weight gain

Loss of balance

Drowsiness

Difficulty in finding the right words

Fatigue

Irritability

Dry Mouth

Nausea etc

Can these drugs be stopped suddenly?

No. Stopping the medicines used to treat your TN pain is as challenging as starting you on them.

Because of the need to titrate your dosages, or shift to a different medication you need to know this.

We need to change dosage or type of medicine if you are not responding,   nature of pain has changed. a nerve block injection has failed or pain has recurred.

Typically, the medicines in high doses are tapered off over few weeks before stopping completely. This is especially true after you have undergone a successful MVD surgery. Dr Jaydev Panchwagh and his team have a specific protocol for tapering these drugs.

So, what can be expected during withdrawal?

Typically, one notices dizziness, nausea, increased pain, agitation, confusion, disorientation, violent dreams, tremors, irritability etc

Where can I find more information on the medicines?

We have an entire website dedicated to treatment of Trigeminal neuralgia pain. You can find information here.

Is there any alternative to medicines?

Yes, people try naturopathy, Homeopathy, Ayurveda, or Acupuncture, Acupressure and others.

Some people believe exercises help them. Some make adjustments in food.

What if medicines for treating the pain of trigeminal neuralgia have stopped working?

Do not worry! There are alternative treatments available. Nerve injections and Gamma knife procedures are nerve destructive procedures. Their effect is generally temporary. The success rate for pain relief is also less as compared to surgery.

Surgery for TN is called Microvascular Decompression (MVD surgery). It is generally a nerve preserving procedure, offers the potential of permanent pain relief. You can learn more about this here and here.

Dr Jaydev Panchwagh is the chief Neurosurgeon and Director of the Centre of excellence for MVD surgery in Pune, India. He has been keenly focused on MVD surgery for nearly twenty years and has operated on patients from more than 22 states in India, and about 13 countries around the world. He has performed more than 1900 MVD surgeries as of this date.

You can find more information on his work here.

Trigeminal neuralgia medication-how to take them?

Trigeminal neuralgia medication, at least the majority of them, are anti-convulsants.

“How to take them-Trigeminal neuralgia medication?”

Can I take TN medication when I feel the pain coming on?

Can I add more drugs during a Trigeminal neuralgia attack?

Do I have to continue taking the Trigeminal neuralgia medicines even if I have no or minimal pain?

These are all questions that frequently come to the patients’ minds.

What is essential to understand is that TN medicines are not straight-forward pain-killers. They are primarily anti-convulsants or brain numbing medications. Once the first pill is consumed, it takes a few hours to reach the blood. The liver simultaneously metabolizes the drug, while some of it also reaches the brain to act upon. So in effect, the blood level reduces. Over a period of the next few hours, the blood level will become zero. Before this happens, we need to consume another pill to increase and maintain the blood level. If this does not happen, there is no effect on the pain as well.

In short, regular medication is essential to maintain a particular blood level of the drug, so that it calms the brain/ nerve. This calming effect means that they do not respond to pain signals, and therefore have a neuralgic-pain-reducing effect.

Another key point to be noted is that the dosages need to be very gradually increased (and decreased also).

What happens if I take too many TN pills?

Well, you will certainly start manifesting all the side-effects of these anti-convulsants, like drowsiness, dizziness, imbalance, mental clouding, memory loss, depression etc. This is why, their dosages have to be adjusted by your doctor, who will determine what is right for you. One typically starts with the lowest dosage twice or thrice a day. This may be increased to maximum doses four times a day.

What happens if I miss a couple of doses of TN medication?

The blood level reduces, and you may experience break-through pain.

Allergic reactions to Trigeminal neuralgia medication

When starting off drugs to control TN pain for the first time, one has to be aware of and be on the lookout for allergic reactions. Though rare, it is not unheard of. I have come across a few patients in my practice. Typically they are in the form of skin rashes. These may be the harbinger of a very serious and potentially fatal Stevens-Johnson syndrome. If one notices skin rashes on consuming TN medication, please inform your doctor immediately and stop taking it.

What are the commonly used medication for trigeminal neuralgia?

What other drugs than anticonvulsants are useful for TN pain?

Is TN permanent?

What are some of the FAQs about TN?

Is there a cure for Trigeminal neuralgia?

Who is Dr Jaydev Panchwagh?

Youtube videos explaining in detail about Trigeminal neuralgia

Can I hear some patient testimonials? MicroVascular Decompression surgery to cure Trigeminal neuralgia.

How do I contact Dr Jaydev Panchwagh?

Is Trigeminal neuralgia hereditary?

For those of you who are wondering whether Trigeminal neuralgia is hereditary, the short answer is ‘ not really’. Having said that, there are cases reported where TN runs in families.

Can Trigeminal neuralgia be Familial?

Familial TN is unusual by all means. It is likely to be less than 2 or 3% of all TN patients. It is possible that patients inherit their familial ‘make-up’ of blood vessel contours or laxity, or lengths…we don’t know. Generally the familial type of Trigeminal neuralgia is on the same side in all affected family members.

Can Trigeminal neuralgia be inherited? Can TN be genetically transmitted?

The chances are so slim, that it’s not worth losing good sleep over it.

Have I seen a case of familial Trigeminal neuralgia?

‘No. I have only read case reports. It is likely that this condition is so rare, that one need not be too worried about it.’ Dr Jaydev Panchwagh answers.

Can children be affected with Trigeminal neuralgia?

Though it is unusual, it is not impossible. Diagnosing TN in children may be a problem, because they may not be able to express their problem clearly.

Parents ought to be more observant and help in establishing patterns.

There are reports of Microvascular Decompression surgery being done even in young children to treat them of the Trigeminal neuralgia pain.

My father and I both have Trigeminal Neuralgia. Is this hereditary? Will my children also have it?

It is possible that there are certain anatomical variations in either the brain and skull, or in the blood vessels that have predisposed both of you to have it. We just have to wait and see if it gets passed on to the next generation.

The youngest patient Dr Jaydev Panchwagh, a renowned Indian neurosurgeon  has operated on is a girl of 22 years, who had been having it for five years. The operation was performed at his centre for MVD in Pune, India.  With an experience of more than a thousand trigeminal neuralgia surgeries, he is one of the best neurosurgeons for such delicate and specialized operations.

You may watch his Youtube channel for more on MVD surgery for Trigeminal neuralgia treatment.